Juvenile xanthogranuloma
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
References
Juvenile xanthogranuloma (JXG) ke boemo bo atileng haholo mme ke mofuta oa non-Langerhans cell histiocytic disorder hangata ho bana. Hoo e ka bang 75% ea linyeoe, maqeba ana a hlaha nakong ea selemo sa pele sa bophelo, 'me bakuli ba fetang 15-20% ba na le bona ho tloha tsoalong. Le hoja e sa tloaeleha ho batho ba baholo, JXG e atisa ho hlaha hangata ho batho ba lilemo tse mashome a mabeli ho isa ho tse mashome a mararo, 'me bakuli ba bangata ba baholo ba na le leqeba le le leng feela. Ha e le hantle, e bonahala e le makukuno a tiileng a le mong kapa a mangata a 'mala oa lamunu-sootho, haholo sefahlehong, molala le 'mele o ka holimo. Maqeba a molomo ha a tloaelehe empa a ka 'na a hlaha e le lesela le mosehla mahlakoreng a leleme kapa libakeng tse ling tsa molomo, mohlomong le baka liso le ho tsoa mali. Hangata maqeba a letlalo ha a bake matšoao 'me a atisa ho ikela a le mong ka lilemo tse ngata. Le hoja e le ntho e sa tloaelehang, ho ameha ha mahlo ke taba e tloaelehileng ka ho fetisisa ka ntle ho letlalo, e lateloa ke ho ameha ha matšoafo. Ocular JXG hangata e ama leihlo le le leng feela 'me e etsahala ho bakuli ba ka tlase ho 0. 5 % ea bakuli, le hoja hoo e ka bang 40% ea ba nang le ts'oaetso ea mahlo le bona ba na le maqeba a mangata letlalong ha ba fumanoa.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) ke mafu a sa tloaelehang, a kotsi ao e leng karolo ea sehlopha se seholo sa non-Langerhans cell histiocytoses. Hangata li hlaha e le lesela le le leng kapa a mangata a khubelu kapa a mosehla, hangata a fumanoang hloohong kapa molaleng. Bongata ba li-JXG li hlaha nakong ea tsoalo kapa nakong ea selemo sa pele sa bophelo. Le hoja e le ntho e sa tloaelehang, ka linako tse ling li ka ama libaka tse ka nģ'ane ho letlalo, ka ho ameha ha mahlo e le ntho e lokelang ho shebelloa ho latela lingoliloeng tse teng. Ka kakaretso, li-JXGs letlalong li itsamaela ka botsona 'me hangata ha li hloke phekolo.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Leqeba la mahlo le bonahala ho batho ba ka bang 10% ba nang le JXG mme ba ka ama pono ea bona. Le hoja maqeba a letlalong hangata a nyamela ka tšohanyetso, ke ka seoelo maqeba a mahlo a ntlafetseng 'me a hlokang phekolo.